Gastroparesis and functional dyspepsia: excerpts from the AGA/ANMS meeting.

Motility and Functional Disorders of the Stomach: Diagnosis and Management of Functional Dyspepsia and Gastroparesis

What comes after macrolides and other motilin stimulants?

Delayed gastric emptying is often considered the major pathophysiological mechanism underlying symptoms in both functional dyspepsia and diabetic gastroparesis. Studies have reported a significant delay in the gastric emptying rate of solids in up to 50% of patients with functional dyspepsia and in up to 75% of patients with type 1 diabetes. 2 Prokinetic agents, including metoclopramide, domper...

The GI Surgeon and Gastroparesis

54 OVERVIEWS OF GASTROPARESIS Gastroparesis is characterized by delayed or impaired passage of gastric contents in the absence of mechanical obstruction. Symptoms vary and include nausea, vomiting, bloating, and abdominal pain. The symptoms and clinical presentation of gastroparesis is reflective of its pathogenesis, severity, and association with predisposing or associated conditions. Gastropa...

New vistas on gastrointestinal motility: from physiology to therapy an international symposium in Rome.

like nausea, vomiting, postprandial fullness, abdominal bloating, abdominal discomfort, heartburn, constipation and diarrhea. It is well known that these symptoms are not always brought about by structural diseases of the gastrointestinal tract. They can, for example, be caused by alterations of gastrointestinal motility and/or sensation. These disorders affect an important percentage of the po...

Diagnosis and treatment of chronic gastroparesis and chronic intestinal pseudo-obstruction.

Chronic gastroparesis and CIP are debilitating disorders that are difficult to treat with currently available therapies. Failure of proper migration and differentiation of enteric neurons or ICC can result from specific genetic mutations and lead to phenotypes of CIP with or without concomitant gastroparesis. Intestinal dysfunction in diabetes may reflect a depletion of NO production (and perha...